Establishing immunogenicity and safety of needle-free intradermal delivery by nanoporous ceramic skin patch of mRNA SARS-CoV-2 vaccine as a revaccination strategy in healthy volunteers.

Prins MLM, Prins C, de Vries JJC, Visser LG, Roukens AHE.
Virus Res. 2023 Sep;334:199175. doi: 10.1016/j.virusres.2023.199175. Epub 2023 Jul 21.PMID: 37473964

Nanoporous microneedle arrays seamlessly connected to a drug reservoir for tunable transdermal delivery of memantine.

Vos PJ, Kuijt N, Kaya M, Rol S, van der Maaden K.
Eur J Pharm Sci. 2020 Jul 1;150:105331. doi: 10.1016/j.ejps.2020.105331. Epub 2020 May 26.

Vaccination with influenza hemagglutinin-loaded ceramic nanoporous microneedle arrays induces protective immune responses.

Schepens B, Vos PJ, Saelens X, van der Maaden K.
Eur J Pharm Biopharm. 2019 Mar;136:259-266. doi: 10.1016/j.ejpb.2019.02.002. Epub 2019 Feb 5.PMID: 30731115

Nanoporous Microneedle Arrays Effectively Induce Antibody Responses against Diphtheria and Tetanus Toxoid.

de Groot AM, Platteel ACM, Kuijt N, van Kooten PJS, Vos PJ, Sijts AJAM, van der Maaden K.
Front Immunol. 2017 Dec 13;8:1789. doi: 10.3389/fimmu.2017.01789. eCollection 2017.PMID: 29375544

Microneedle-based drug and vaccine delivery via nanoporous microneedle arrays.

van der Maaden K, Luttge R, Vos PJ, Bouwstra J, Kersten G, Ploemen I.
Drug Deliv Transl Res. 2015 Aug;5(4):397-406. doi: 10.1007/s13346-015-0238-y.PMID: 26044672

Controlled release of a model vaccine by nanoporous ceramic microneedle arrays.

Boks MA, Unger WW, Engels S, Ambrosini M, Kooyk Yv, Luttge R.
Int J Pharm. 2015 Aug 1;491(1-2):375-83. doi: 10.1016/j.ijpharm.2015.06.025. Epub 2015 Jun 23.PMID: 26116016

Ex vivo evaluation of a microneedle array device for transdermal application.

Indermun S, Choonara YE, Kumar P, du Toit LC, Modi G, van Vuuren S, Luttge R, Pillay V.
Int J Pharm. 2015 Dec 30;496(2):351-9. doi: 10.1016/j.ijpharm.2015.09.070. Epub 2015 Oct 21.PMID: 26453791

Insertion Process of Ceramic Nanoporous Microneedles by Means of a Novel Mechanical Applicator Design.

Hartmann XH, van der Linde P, Homburg EF, van Breemen LC, de Jong AM, Luttge R.
Pharmaceutics. 2015 Nov 18;7(4):503-22. doi: 10.3390/pharmaceutics7040503.